Share LinkedIn Email Share on Twitter Pinterest Share on Facebook A molecule that enables strong communication between our brain and muscles appears to also aid essential communication between our neurons, scientists report.On the surface of our numerous star-shaped brain cells called astrocytes, they have found the molecule LRP4 is important in ensuring healthy levels of a brain chemical that enables learning and memory, said Dr. Lin Mei, chairman of the Department of Neuroscience and Regenerative Medicine at the Medical College of Georgia at Augusta University and Georgia Research Alliance Eminent Scholar in Neuroscience.The brain chemical, or neurotransmitter, is glutamate, the most important excitatory neurotransmitter in the brain, which essentially means it is passed between neurons to help one activate the next. It was known that astrocytes could regulate or modulate brain cell communication by adjusting levels of glutamate. But now, the MCG scientists have shown that LRP4 is in those astrocytes, and that without it, glutamate release is dramatically reduced. Mice are intellectually impaired and have difficulty with movement, Mei said of the findings he characterizes as “unexpected.” One benefit was protection from seizures because of the reduced excitability of neurons. Removing LRP4 from nearby neurons did not yield the same negative effects.While much work remains, Mei and his colleagues believe the work published in the journal Nature Neuroscience provides new insight into the critical regulation of neurotransmitters that enable neurons to take action as well as potential therapeutic targets for one day helping individuals with intellectual disabilities.Once made, glutamate gets passed from one neuron to the next via synapses, much like the arm of one neuron reaching out to hand something to the next. Dysfunction of synapses is associated with a host of neuropsychiatric disorders such as epilepsy, addiction, schizophrenia and autism.Taking LRP4 out of the equation messes up the delicate balance, the scientists have found. Without it, levels of ATP, a natural energy source for cells that also inhibits glutamate release, also dramatically increase. In fact, regulating ATP levels is one way astrocytes help regulate the level of neurotransmitters, Mei said. But in this scenario, too much ATP translates to too little glutamate. Blocking the receptor ATP eventually activates ameliorates the negative impact that high levels had on the mice.“When you take LRP4 out of astrocytes, ATP levels released by those astrocytes go super high, which suppresses glutamate transmission,” Mei said.Astrocytes are the most common of a type of brain cell called glial cells. In fact, astrocytes account for about half of all the cells in the brain, Mei said. While the brain actually has more glial cells than neurons, glial cells were long thought to provide only structural support to the neurons, much like cement supports a house. “That view has been changed and is changing,” said Mei. Now it’s clear that glial cells, like astrocytes, have a role in neurodevelopment and longer-term in regulating communication between two neurons.In the neuromuscular juncture, Mei’s lab found several years back that LRP4 on the muscle cell surface is a receptor for agrin, a protein that motor neurons release to direct construction of the nerve-muscle juncture. His lab later identified antibodies to LRP4 and agrin as new causes of myasthenia gravis. The new research indicates that release of ATP by astrocytes is also regulated by agrin signaling.
In rTMS, an electromagnetic coil is placed on the scalp and uses magnetic pulses to cause neurons (nerve cells) in the brain to activate. The goal is to train the neurons to perform better in the future. The rTMS treatment has no, or only mild side effects: some people report a slight headache that is easily treated with a pain relief pill. And the risk of seizure is very low. (Individuals with a history of epilepsy and/or seizures are excluded from rTMS treatments for that reason.)‘I remember’Our very first patient was a challenging 82-year-old lady at a relatively advanced stage of Alzheimer’s, who hated the treatment. Every time I asked her if she had children, she said: “Not yet; I’m still in my twenties!”On the seventh day of the treatment, in the middle of session, she asked us to stop. Her husband tried to calm her and convince her to continue, saying: “Didn’t you want to remember our children?”She replied: “But I do remember Susan, Sam and Dona; why do I need this stupid treatment?”That moment was what I had dreamed to see in my late mother: the way she used to be, even for a few minutes. That patient’s cognitive state did not show any significant improvement over the course of treatment. However, her short moment of memory retrieval encouraged me to continue the rTMS treatment study on others as well — particularly on those at earlier stages of Alzheimer’s.One thing to note and remember is that Alzheimer’s is a progressive degenerative disease. If we intervene to plateau the state of the patient or slow the progression, that is indeed an improvement and can be considered a positive effect of the treatment.How rTMS treatment for Alzheimer’s disease works and is administered. (Zahra Moussavi) Alzheimer’s disease is considered a global challenge of the century. Alzheimer’s disease is a thief. It comes and takes away the most precious memories with which people identify themselves. It is a very clever thief. People whom it affects don’t even remember what they have lost — they just feel lost; lost in space and time.Alzheimer’s can affect anybody: intellectuals, professors, artists, musicians and handymen. My mother’s Alzheimer’s motivated me to start the very first Repetitive Transcranial Magnetic Stimulation (rTMS) treatment for Alzheimer’s in Canada.The treatment is a non-invasive procedure that doesn’t involve any medication. This technology has been used to successfully treat depression, and it is also being studied for a number of other neurological conditions (for example, Parkinson’s, concussion and stroke). In our pilot study, we gave a maintenance treatment every three months, to seven of our initial 10 participants, for up to a year and a half. Our results showed that as long as patients were receiving the treatment, they did not decline. Some improved slightly.As soon as we stopped the treatment (due to lack of funding), all patients started to show some decline. Three of them declined so severely that, within three months of stopping treatment, they ended up in a nursing home and passed away within a year.Overall, our pilot study and similar small-sample studies around the globe showed encouraging results of rTMS treatment on Alzheimer’s, especially when it was applied at early and moderate stages.Encouraging steps to new Alzheimer’s treatmentAs a result of those pilot studies, the Weston Brain Institute has now funded the very first large placebo-controlled double-blind study of rTMS treatment on Alzheimer’s. This is a collaboration of three universities: University of Manitoba, McGill University and Monash University. The team includes engineers, psychiatrists, clinical psychologists, neurologists and statisticians.The study is to investigate the effect of rTMS treatment on Alzheimer’s patients at early and moderate stages. All participants have to be diagnosed by one of the study doctors. And there are several assessments for before and after treatment to assess the efficacy of the treatment and how long it may last.While this current study is an encouraging step towards finding new treatment methods for Alzheimer’s, there are several other parameters in the rTMS treatment protocol whose investigation is not currently funded. They include: the method by which rTMS pulses are delivered, the location of the stimulation and the duration of treatment. Our current study investigates only the standard protocol of rTMS treatment. We hope after some preliminary results to apply for, and receive, more funding to continue the research.The number of people affected by Alzheimer’s disease is on the rise. Alzheimer’s not only steals precious aspects of life from affected individuals but also from their families. Alzheimer’s forces the relatives of a patient to hopelessly watch a tragedy progress over a prolonged period of time, day after day.Alzheimer’s disease is a multifold condition that requires a multidisciplinary approach for its treatment. It is only through our collective efforts that we can hope to find a solution for such a grim and dreadful disease. Despair may fly on the wings of morning; out of the heart of darkness comes the light.By Zahra Moussavi, Professor of Biomedical Engineering, University of ManitobaThis article was originally published on The Conversation. Read the original article. Pinterest Email LinkedIn Share on Facebook Share Share on Twitter read more
A hunting rifle is no match against an assault rifle, which is designed for a rapid and continuous deadly attack due to the automatic chambering of rounds after each trigger pullWeapons are designed to achieve a certain purpose and should be restricted to that purpose.Arming guards and teachers in a school is a moronic solution against a determined suicidal individual, heavily armed with multiple high-capacity magazines.Listen to the Florida students who are speaking so eloquently about the “war-like” destructive nature of what they witnessed. Then listen to NRA’s Wayne LaPierre and Dana Loesch speaking at the Republican CPAC meeting, blaming the problem on anything and everyone but the free flow of guns.Call our politicians and tell them that you will not vote for those who are unwilling to make sensible legislative changes to our gun laws.BILL SMITHMechanicvilleMore from The Daily Gazette:EDITORIAL: Find a way to get family members into nursing homesEDITORIAL: Urgent: Today is the last day to complete the censusPolice: Schenectady woman tried to take car in Clifton Park hours after arrest, release in prior the…Foss: Should main downtown branch of the Schenectady County Public Library reopen?EDITORIAL: Beware of voter intimidation Categories: Letters to the Editor, OpinionLegislation will never be passed that takes away the right of citizens to protect themselves, their family and home; or for hunting and target shootings.But in the 2008 Supreme Court ruling, Justice Scalia said, “Like most rights, the right secured by the Second Amendment is not unlimited …” It is “not a right to keep and carry any weapon whatsoever in any manner whatsoever and for whatever purpose.”A handgun is no match against a rifle, for it isn’t anywhere near as accurate. read more
CLEVELAND — Eaton Corp. has named Steve Boccadoro vice president – sales and marketing, effective Aug. 15. He will report to Alexander Cutler, Eaton chairman and CEO. AdvertisementClick Here to Read MoreAdvertisement “Steve brings great experience in managing large sales and marketing organizations and working with some of Eaton’s largest channel partners,” Cutler said. “We are looking forward to having Steve join the senior leadership team.” Boccadoro succeeds Jeffery Krakowiak, who has been named vice president and general manager – Canada for its Electrical Sector Americas Region, also effective Aug. 15. Boccadoro joined Eaton in 1987 from Peat Marwick, where he was an audit manager. Since joining Eaton, Boccadoro has held positions of successively greater responsibility in both Canada and the U.S., including controller, plant manager, marketing manager and, most recently, vice president and general manager – Canada. Boccadoro holds a bachelor’s degree in commerce from McMaster University in Ontario, Canada, and is a professional chartered accountant. He will be based at Eaton’s world headquarters in Cleveland, Ohio. For more information, visit www.eaton.com.,Lubrication Specialties Inc. (LSI), manufacturer of Hot Shot’s Secret brand of performance additives and oils, recently announced the expansion of senior leadership. Steve deMoulpied joins LSI as the company’s chief operating officer (COO). AdvertisementClick Here to Read MoreAdvertisement With more than 20 years of experience across multiple industries and functional areas, deMoulpied has particular expertise in organizations with complex technical products. Combined, his prior positions have required a spectrum of skills in corporate strategy, operations improvement, product quality, and revenue cycle management. He has an impressive history of utilizing data driven problem solving (Lean Six Sigma) and project management (PMP and CSM) to achieve strategic goals surrounding customer satisfaction, operational efficiency and improved profit. DeMoulpied has a Bachelor of Science degree in Engineering Management from the United States Air Force Academy and a Master of Business Administration degree from the University of Dayton in Marketing and International Business. He served six years with the USAF overseeing the development of technology used on fighter aircraft and the E-3 Surveillance aircraft, finishing his career honorably as Captain. DeMoulpied comes to LSI from the Private Client Services practice of Ernst & Young where he managed strategy & operations improvement engagements for privately held client businesses. Some of his prior roles include VP of strategic development, director of strategic initiatives, and Lean Six Sigma Master Black Belt at OptumHealth, UnitedHealth Group’s health services business, as well as Lean Six Sigma Black Belt at General Electric, where he applied operations improvement principles to customer service, supply chain and product development. A successful entrepreneur, deMoulpied is also the founder of PrestoFresh, a Cleveland-based e-commerce food/grocery business. LSI President Brett Tennar says, “Steve’s success in developing operational strategies that improves the bottom line, builds teamwork, reduces waste and ensures quality product development and distribution checks many of the boxes of what we were looking for in a COO. This, coupled with his career in the Air Force working with highly technical systems and his in-depth understanding of Lean Six Sigma and Business Process Management sealed our offer. As our tagline states, our products are Powered by Science. This data driven approach is one reason why our company has grown exponentially as we employ the most advanced technology to product development. I am confident that Steve is the right person to drive operational strategy for our diverse and growing brands.” Advertisement read more
The United Nations on Friday launched a global push for a coronavirus vaccine as President Donald Trump triggered an uproar by suggesting patients be treated with disinfectant and the US death toll passed 50,000.Across the Muslim world, hundreds of millions of faithful opened the Ramadan holy month under stay-at-home conditions, facing bans on prayers in mosques and on the traditional large gatherings of families and friends to break the daily fast. With effective medical treatments still far away, UN Secretary General Antonio Guterres said defeating the pandemic will require global organizations and world leaders joining forces with the private sector to develop and distribute a novel coronavirus vaccine. “We face a global public enemy like no other,” Guterres said. “A world free of COVID-19 requires the most massive public health effort in history.”The UN chief’s appeal came a day after the US president prompted an outcry with his suggestion that industrial cleansers be used to treat patients.”Is there a way we can do something like that, by injection inside or almost a cleaning?” Trump mused during a televised briefing. “It sounds interesting to me.”As experts — and disinfectant manufacturers — rushed to caution against any such dangerous experiment, the president tried to walk back his comments claiming he had been speaking “sarcastically.” The hardest-hit country by far in the global pandemic, the US had recorded 51,017 deaths and more than 890,000 infections.Early stages Confirmed coronavirus cases hit 2.77 million worldwide Friday, with deaths at 193,930.New reported cases seem to have leveled off at about 80,000 a day, as distancing measures have taken root and the daily death toll in Western countries appeared to be falling — a sign hopeful epidemiologists have been looking for.Yet other nations are still in the early stages of the fight and the World Health Organization has warned strict measures should remain in place.New cases were accelerating in countries with low testing or late and limited mitigation like Russia, Sudan, Somalia, Nigeria, the Maldives and Guatemala.In Argentina, with some 3,400 cases and 167 deaths so far, prisoners rioted and demanded their release from a Buenos Aires jail on Friday after confirmation of a coronavirus case inside the facility.Global vaccine cooperation In Geneva, the WHO hosted a virtual conference on global cooperation to develop a vaccine, together with French President Emmanuel Macron, Germany’s Angela Merkel, the wealthy Gates Foundation and GAVI, the global vaccine alliance.”The world needs the development, production and equitable delivery of safe and effective COVID-19 vaccines, therapeutics and diagnostics,” Guterres said.”Not a vaccine or treatments for one country or one region or one-half of the world, but a vaccine and treatment that are affordable, safe, effective, easily administered and universally available, for everyone, everywhere,” he said.Notably absent from the group were leaders of China, where the virus surfaced, and the United States, which has accused the WHO of not warning quickly enough about the original outbreak in China. Mecca’s Grand Mosque deserted The pandemic put a damper on the opening of Ramadan, during which Muslims around the world fast during daylight hours and then, after evening prayer, dine with family and friends.In the Saudi holy city of Mecca, the Grand Mosque, usually packed with tens of thousands of people during Ramadan, was deserted as religious authorities suspended the year-round umrah pilgrimage.”We are used to seeing the holy mosque crowded with people during the day, night, all the time… I feel pain deep inside,” said Ali Mulla, the muezzin who gives the call to prayer at the Grand Mosque.But clerics and conservatives in some countries including Bangladesh, Pakistan and Indonesia — the world’s largest Muslim-majority nation — have pushed back against social distancing rules, refusing to stop gatherings in mosques.Several thousand attended evening prayers on Thursday at the biggest mosque in the capital of Indonesia’s conservative Aceh province, and there were similar scenes in many sites in Pakistan.Economic contraction The economic devastation wreaked by the global lockdown is huge, with the world facing its worst downturn since the Great Depression of the 1930s.Russia’s central bank said its economy would shrink up to six percent this year, hit doubly by the coronavirus and the plunge in oil prices.In the United States, the Congressional Budget Office forecast GDP will contract by 12 percent in the April-June quarter and the federal deficit, due to massive stimulus spending, will explode to $3.7 trillion in 2020.Trump on Friday signed the newest financial support package, providing $483 billion for small businesses and hard-pressed hospitals.Across the United States, state leaders were weighing whether to start gradually lifting lockdown measures.But the governor of Georgia was under attack for going so far as to approve the opening of businesses where social distancing is difficult, like gyms, hair salons and tattoo parlors.”If I don’t cut hair I don’t make money,” said mask-wearing Atlanta barber Chris Edwards, as he trimmed the hair of an unmasked client. “We’re being safe, we’re being clean, it’s all you can do.”Europe In Europe, leaders haggled over their own relief package that could top one trillion euros, as the European Central Bank chief warned of the risk of “acting too little, too late.”The 27-nation European Union has agreed to ask the bloc’s executive arm to come up with a rescue plan by May 6, sources told AFP.The crucial economic discussions come as parts of Europe slowly loosen restrictions after progress on reducing the number of new infections.Belgium became the latest to ease, announcing Friday that businesses and schools will gradually reopen from the middle of May.”The spread of COVID-19 has been slowed down, but the virus has not disappeared,” Prime Minister Sophie Wilmes said.Experts have warned of a possible second wave of infections, particularly in the fall when temperatures cool.Virologist Christian Drosten of Berlin’s Charite Hospital said the coronavirus could return with a “totally different force.”Topics : read more
Bauer’s vast experience in the compressor market, coupled with its commitment to produce valuable innovations, has resulted in great development and today the company prides itself in being fully specialised in the markets of high-pressure breathing air products, GSA/military breathing air products, industrial air and gas products, plastics technology, natural gas, and inert gas compression.The company began its North American journey back in 1976, when it opened its first facility outside of Germany in Norfolk, Virginia, which has since grown from hosting just two employees to over 250 and now stands Bauer’s headquarters.“The Bauer Norfolk, Virginia, facility is the largest systems packaging facility outside of Germany, followed by packaging facilities in China, India, UK, Australia and France,” Tony Bayat, President of Bauer Compressors told gasworld in an exclusive interview. “We did a major expansion of the US facility back in 2014 and our operations in China and India are also growing.”Today, Bauer stands as a 100% vertically integrated enterprise that controls every aspect of the design manufacturing process, both of which have greatly contributed to its respectable reputation.Although the company is continuing to grow both its number of facilities and employees, all of the company’s high-pressure compressor bareheads are still manufactured in Germany, but now at its new state of the art facility in Geretsried, which is 35 km south of the original Munich plant. Once manufactured, the compressors are then packaged into complete solutions in various Bauer facilities around the world.Talking about the company’s high-pressure offering, Bayat, said, “In the high-pressure segment (2500-7000 psig) we produce compressors from 5hp all the way to 350hp. We build a lot of speciality systems for various breathing air applications which require ultra-purified air. Therefore, we have a lot of in-house expertise of not only compression but purification and verification (gas analysis) as well.”“In the industrial sector, we provide complete solutions for compressed natural gas, biogas, nitrogen production and compression and various high-pressure air systems used in various industries. In the rare gas category, we provide complete recovery and compression systems for helium as well as argon.”Trends Although its traditional high-pressure offering continues to be at the forefront of the company, Bayat told gasworld that the company is also seeing huge demand for data related systems.Bayat commented, “We are currently focusing heavily on digital transformation. Our state- of-the-art Bauer ConnectTM remote telemetry and control app with Al predictive algorithm allows customers to remotely operate and monitor their Bauer products from any internet- connected mobile device.”“Besides providing our customers with push notifications related to important operating parameters we are offering an array of standard and customised historical reporting related to our customers’ performance criteria.”“Through Al, the system automatically monitors and analyses important trends and generates feedback on corrective actions. We see this as a continuation of what has made Bauer successful for over 75 years, i.e. our focus on developing state-of-the-art high-pressure solutions for our customers which are geared to their specific performance needs and which are designed to add exceptional value to their operations above and beyond just compression.” read more
SBM Offshore informed that the FPSO Cidade de Saquarema is formally on hire after achieving first oil.The FPSO is installed in the Lula field (BM-S-11 contract) in the pre-salt province offshore Brazil.It will operate under a 20-year charter with Tupi BV as well as an operations contract with the BM-S-11 consortium.The BM-S-11 block is under concession to a consortium comprised of Petrobras (65%), BG E&P Brasil Ltda – a Royal Dutch Shell subsidiary (25%) and Petrogal Brasil S.A. (10%).The FPSO is owned and operated by a joint venture owned by affiliated companies of SBM Offshore, Mitsubishi Corporation, Nippon Yusen Kabushiki Kaisha, and Queiroz Galvão Óleo e Gás S.A.
Six of the ships are 9,500 dwt multipurpose cargo and container vessels ordered by a European owner from Yangfan Group Co Ltd. The other four are 18,000 dwt multipurpose vessels ordered by an undisclosed European owner from Wuhu Xinlian Shipbuilding. MacGregor, owned by Cargotec, is supplying hatch cover design and key components and fixed container securing equipment for deck and holds for both series. “Close co-operation between MacGregor’s different product areas has been one of the key factors in our success” said Svante Lundberg, sales manager for cranes. “Another important factor is working closely with customers early on in projects, which enables us to provide the most effective and functional solution for their particular cargo handling needs”. The six 9,500 dwt ships on order at Yangfan Group will each carry two GLH heavy-lift cranes, while the four 18,000 dwt multipurpose vessels will each carry three. The ships are designed to carry containers in the holds and on hatch covers, bulk cargoes, heavy cargoes, steel coils, project cargo (large and heavy), timber and palletised cargo. read more
Instead of a 30-day frequency, AAL and Swire will be offering a joint scheduled breakbulk liner service with an improved 20-day frequency and an additional five base ports.The new service will connect the Asian ports of Tianjin, Qingdao and Shanghai (China), Incheon and Pusan (South Korea), Kaohsiung (Taiwan) and Phu My (Vietnam), with the Australian ports of Brisbane, Newcastle, Geelong, Melbourne, Bell Bay and Gladstone. Additional ports, including Dalian, Kobe, Townsville, Mackay and Portland, will be available on inducement.AAL’s two 31,000 dwt multipurpose heavy lift vessels, each with a combined lifting capacity of 700 tonnes – AAL Hong Kong and AAL Shanghai – will continue to be deployed on the route. Space can also be booked directly through AAL on two smaller vessels being deployed by Swire.Through the slot sharing agreement, both AAL and Swire will work together to coordinate vessels, timings and port calls. However, both companies will retain their individual booking and marketing services for their respective customers.Christophe Grammare, managing director of AAL’s liner services division, explained the reasons behind the cooperation.”The general market is not at its best at the moment, and Australia is relatively low. We are just coming down from a long mining boom and a number of LNG projects are coming to a close, while the steel industry is suffering due to anti-dumping measures.”In addition, the strong competition and over capacity in the container industry has led to very cheap container rates, meaning that some customers are choosing to ship breakbulk cargo on containerships rather than specialist vessels.”Grammare admitted that this was not a temporary concern: “We expect the Australian market to remain down for the next year or two. There are a limited amount of projects to boost the economy, and there are no new developments on the cards.”As a result we have been working with Swire, and due to the market conditions, we have agreed to coordinate our services, which will result in cost savings for both of us. We either had to downscale our services or create a proactive partnership.”Having said that, we have structured this agreement to deliver fundamental benefits to our liner customers, including an increased number of base ports (increased to 13), improved transit times on individual sailings and superior frequency – from 30 days to 20 days.”When asked whether AAL would be developing similar partnerships on the surrounding trade lanes, Grammare explained that this would not be necessary. “There is no further development on the cards. In the Asia Pacific region, Swire and AAL are reasonable complimentary – this is the one service in which we were overlapping.”However, in terms of general consolidation in the shipping industry, Grammare was positive about the prospect of additional partnerships. “At the end of the day, consolidation is what the industry needs.”Grammare also confirmed that this new agreement between Swire and AAL would not be affected by Swire’s existing partnership with Rickmers-Linie, which HLPFI reported about on June 8, 2015.He explained that Swire was the obvious choice in terms of a partner in the Asia Pacific region. “With regards to business models, Swire is the closest thing to what AAL does.” Moreover, he continued, both Swire and AAL offer a breakbulk liner service – something that Grammare believes is the best possible option in the declining market. “In the boom period, there were lots of tramp services in Australia, but now that volumes have dropped, it is a risky business for tramp operations. Therefore, a liner concept is the best option.”Grammare concluded: “We are acknowledging that the market conditions are different, so we want to make our service viable in the existing market, rather than wait for ‘maybes’ and conditions to improve.” www.aalshipping.comwww.swireshipping.com read more
Set over two levels, the house has multiple living areas, a custom-built kitchen plus elevated decks to the front and rear of the home. Now on the market, it is up to the court of public opinion — or rather, buyers — to pass judgment, and make an offer. And the Courier Mail understands its already getting plenty of interest. More from newsParks and wildlife the new lust-haves post coronavirus14 hours agoNoosa’s best beachfront penthouse is about to hit the market14 hours ago“We bought the house in the early 1980s. It was built in the 1920s and our understanding is that the owner-builder lived in it until the 70s and then it changed hands a few times before we purchased it,” Mrs Dorney said. Judge Kiernan Dorney QC Picture: Marshall Sarah But when he wasn’t hearing the gory details of a case, he was escaping to the character Queenslander he shared with his wife Bernadette and their three children. Judge Dorney said at the time they had been living at Ferny Hills, and were concerned it was out of their price range. “We fell in love with it. We thought at the time that it was too expensive for us but we could see its potential,” he said.Mrs Dorney said they added rooms and decks, but worked hard to maintain its charm.She said they saw it as a character home, albeit one with “all of the modern inclusions you could ever want”.The four bedroom Queenslander sits on a 622sq m block in one of Brisbane’s prettiest suburbs. A RETIRED district court judge who presided over some of Queensland’s biggest civil and criminal trials is selling his Brisbane character home.Judge Kiernan Dorney QC spent seven years on the bench before retiring in 2017. The lower level is home to two bedrooms, a laundry, cellar and the open plan living room and kitchen, which opens on to a veranda that overlooks the pool.Two more bedrooms including the master bedroom with ensuite and built-in robes are located on the upper floor. This floor is also home to a formal living room, the main kitchen with granite bench tops, 900mm gas cooktop and soft close cabinetry, a formal dining room that opens on to the rear deck, and a study. Outside there is a landscaped backyard and a pool. Mrs Dorney said they had watched their children grow in to adults, and were now proud grandparents, but the time had come to downsize.As for the suburb they have called home for four decades, Judge Dorney said they loved the fact it had a leafy aspect while still being close to the city. “I could leave here at 8.10am and be in my chambers by 8.30am,” he said. “I was close to work but could be at home, look out over the valley to the next ridge, and feel like we were a long way from the city.” read more